| 000 | 01437nam a2200385Ia 4500 | ||
|---|---|---|---|
| 001 | 009188 | ||
| 008 | 141222s9999 xx 000 0 und d | ||
| 040 | _aDB/INS | ||
| 041 | 0 | _aeng | |
| 210 | 1 | 0 | _aAm. J. Med. Genet |
| 245 | 0 | 0 | _aSystematic genetic study of Alzheimer disease in Latin America: Mutation frecuencies of the amyloid ß precuesor protein and presenilin in Colombia |
| 245 | 0 | 0 | _cDiana Arango, Marc Cruts, Orlando Torres … [et.al] |
| 260 | _c2001 | ||
| 300 | _a103-43 | ||
| 300 | _btbls.;grafs | ||
| 362 | 1 | _aVol. 103 (2001) | |
| 520 | _aNearly all mutations in the presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid ß precursor protein (APP) genes lead to early-onset Alzheimer disease (EOAD, onset age at or before 65 years). In order to assess the genetic contribution of these genes i | ||
| 650 | 1 | _aEnfermedad de Alzheimer | |
| 650 | 2 | _aBibliografía del INS4 | |
| 650 | 2 | _aEnfermedades del sistema nervioso | |
| 650 | 2 | _aEnfermedades neurodegenerativas | |
| 650 | 2 | _aPrecursor de proteína-beta amiloide | |
| 651 | _aColombia | ||
| 700 | 1 | _aArango, Diana | |
| 700 | 1 | _aBackhovens, Hubert | |
| 700 | 1 | _aBroeckhovens, Christine Van | |
| 700 | 1 | _aCano, Carlos | |
| 700 | 1 | _aCruts, Marc | |
| 700 | 1 | _aJacquier, Martine | |
| 700 | 1 | _aMatallana, Diana | |
| 700 | 1 | _aMontañes, Patricia | |
| 700 | 1 | _aSerrano, Martha L | |
| 700 | 1 | _aTorres, Orlando | |
| 700 | 1 | _aVillarreal, Elsa | |
| 999 |
_c18607 _d18607 |
||