000 01180nam a2200301Ia 4500
001 005502
008 141222s9999 xx 000 0 und d
040 _aDB/INS
041 0 _aeng
210 1 0 _aJ. Biol Chem
245 0 0 _aInterruption of Escherichia coli Heat-stable Enterotoxin-induced guanylyl cyclease signaling and associated chloride current in human intestinal cells by 2-chloroadenosine
245 0 0 _cScott J Parkinson, Alexey E Alekseev, Luis A Gómez … [et.al]
260 _aPhiladelphia
260 _c1997
300 _a754-8
362 1 _aVol. 272, no. 2 (Jan. 1997)
520 _aDiarrhea induced by Escherichia coli heat-stable enterotoxin (STa) is mediated by a receptor guanylyl cyclase cascade. The present study establishes that an intracellular nucleotide-dependent pathway disrupts toxin-induced cycle GMP (cGMP) production and
650 1 _aEscherichia coli
650 2 _aAdenina
650 2 _aBibliográfia del INS
650 2 _aToxinas bacterianas
700 1 _aAlekseev, Alexey E
700 1 _aGómez, Luis A
700 1 _aParkinson, Scott J
700 1 _aTerzic, Andre
700 1 _aWagner, Frank
700 1 _aWaldman, Scott A
999 _c14925
_d14925