TY - BOOK AU - Alekseev,Alexey E AU - Gómez,Luis A AU - Parkinson,Scott J AU - Terzic,Andre AU - Wagner,Frank AU - Waldman,Scott A TI - Interruption of Escherichia coli Heat-stable Enterotoxin-induced guanylyl cyclease signaling and associated chloride current in human intestinal cells by 2-chloroadenosine CY - Philadelphia KW - Escherichia coli KW - Adenina KW - Bibliográfia del INS KW - Toxinas bacterianas N2 - Diarrhea induced by Escherichia coli heat-stable enterotoxin (STa) is mediated by a receptor guanylyl cyclase cascade. The present study establishes that an intracellular nucleotide-dependent pathway disrupts toxin-induced cycle GMP (cGMP) production and ER -